TY - JOUR AU - Warangkana Chompoopan, AU - Sipanut Silaket, AU - Wichai Eungpinichpong, AU - Suwanna Arunpongpaisal, AU - Niramol Patjanasoontorn, PY - 2018/03/19 Y2 - 2024/03/29 TI - COMPARISON OF HEART RATE VARIABILITY BETWEEN PATIENTS WITH MAJOR DEPRESSIVE DISORDER AND NORMAL SUBJECTS JF - GEOMATE Journal JA - INTERNATIONAL JOURNAL OF GEOMATE VL - 15 IS - 49 SE - Articles DO - UR - https://geomatejournal.com/geomate/article/view/974 SP - 150-154 AB - <p>Major Depressive Disorder is one of the major mental health problems that affect the quality of <br>life of the patients. The reduced heart rate variability (HRV) and elevated heart rate that associated with <br>depression have been found as risk factors for cardiac mobility and mortality. These patients should be assessed <br>regularly on HRV parameters and compare with those of normal subjects. This study aimed to compare heart <br>rate variability between patients with the major depressive disorder and normal subjects. This study was <br>conducted at a psychiatric department in Khon Kaen University, Srinagarind Hospital, Khon Kaen province, <br>Thailand. A cross-sectional analytic study design was used. Forty patients diagnosed with the major depressive <br>disorder (who had been treated with antidepressants) were matched according to age, gender with 40 normal <br>subjects participated. They were assessed on HRV for time domain (standard deviation normal to normal: <br>SDNN, and the root mean square of successive differences: RMSSD) and frequency domain (High frequency: <br>HF, low frequency: LF, and LF/HF ratio) using SA 3000P Digital. The results showed that The HRV in the <br>patients and in the normal subjects were found with SDNN 28.60, 31.44; RMSSD 23.78, 26.73; HF 4.70, 5.04; <br>LF 4.46, 5.01; and LF/HF 1.16, 1.35 respectively. However, No significant difference in the HRV variables <br>between MDD and normal subjects except LF. Findings of this study show that HRV in the treated patients with <br>major depressive disorder seems to be a little lower than the normal subjects. This may be due to the effects of <br>well treated with antidepressants. It is suggested that HRV may be one of the outcome measures for this patient <br>population.</p> ER -